Volunteers Wanted - Lab and Data Mining Research Associates

Our Mission: Flatley Discovery Lab is an independent not-for-profit laboratory for Cystic Fibrosis drug discovery research and development. Our goal is to create patient value by accelerating development of new treatments for CF. We are focused on discovering small molecules that help restore misfolded F508del-CFTR protein functions.

Flatley Discovery Lab, a not-for- profit for Cystic Fibrosis research lab, is seeking volunteers to join our growing team of scientists and researchers in Charlestown, MA.

We will consider candidates from recent graduates to retired professionals.

Available Positions

Literature/Data Mining Researchers who will become part of a ten member team, searching for novel compounds from literature and other subscriber tools. We are currently seeking creative and highly motivated scientists to join our data mining research group. The role will entail using PubMed, SciFinder, GeneGo and other database and/or computational tools to identify cystic fibrosis transmembrane conductance regulator (CFTR) ligands that improve function and trafficking of misfolded F508del-CFTR. This position requires working with a team of researchers but individually selecting compounds that then will undergo biological testing in our lab. Team members will then get to choose and have compounds tested in the lab monthly.


  • BS or MS in a relevant scientific discipline such as biology, pharmacology, chemistry or pharmacy
  • 0-2 years’ experience in a research environment
  • Ability to work effectively in a creative and entrepreneurial environment
  • Good oral, written and presentation skills
  • Experience with text mining or data mining of scientific databases is desired
  • Team oriented, enthusiastic, flexible with good communication and organization skills
  • Would prefer at least a one year commitment

Please send a letter along with your resume to volunteer@flatleydiscoverylab.com


News & Developments

Oct 10, 2013 Flatley Discovery Lab, LLC Nominates Clinical Candidate for Treatment of Cystic Fibrosis
CHARLESTOWN, Mass.--(PRESS ENTITY)—October 10, 2013—Flatley Discovery Lab, LLC today announced that it has nominated FDL169, an orally available small molecule for the treatment of Cystic Fibrosis, as a clinical candidate and initiated IND-enabling st
Dec 3, 2012 Hub lab seeks wider cystic fibrosis cure
Word last week that the U.S. Food and Drug Administration had approved a drug developed by a Cambridge biotech company to treat a rare form of cystic fibrosis that affects about 1,200 people upped the ante for a lab in neighboring Charlestown...
Dec 3, 2012 Venture firm backs start-ups targeting cystic fibrosis
John Flatley, a real estate developer and philanthropist, has founded an investment group called Flatley Venture Capital to back life sciences start-ups with potential treatments for the genetic disease cystic fibrosis. Flatley, who has a close relative w
Dec 3, 2012 WHOI teaming with Flatley Discovery Lab in search for effective treatments for cystic fibrosis.
The Woods Hole Oceanographic Institution (WHOI) has signed a $1.18 million agreement with the Flatley Discovery Lab in Charlestown, Mass., to investigate and supply marine microbial extracts as possible treatments for cystic fibrosis (CF).